The effect of two novel cholesterol-lowering agents, disodium ascorbyl phytostanol phosphate (DAPP) and nanostructured aluminosilicate (NSAS) on the expression and activity of P-glycoprotein within Caco-2 cells

BACKGROUND: Many drugs are substrates for P-glycoprotein (P-gp) and interactions involving P-gp may be relevant to clinical practice. Co-administration with P-gp inhibitors or inducers changes the absorption profile as well as the risk for drug toxicity, therefore it is important to evaluate possibl...

Descripción completa

Detalles Bibliográficos
Autores principales: Sachs-Barrable, Kristina, Darlington, Jerald W, Wasan, Kishor M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195884/
https://www.ncbi.nlm.nih.gov/pubmed/25273894
http://dx.doi.org/10.1186/1476-511X-13-153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195884/
https://www.ncbi.nlm.nih.gov/pubmed/25273894
http://dx.doi.org/10.1186/1476-511X-13-153

Ejemplares similares