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IUTA: a tool for effectively detecting differential isoform usage from RNA-Seq data

BACKGROUND: Most genes in mammals generate several transcript isoforms that differ in stability and translational efficiency through alternative splicing. Such alternative splicing can be tissue- and developmental stage-specific, and such specificity is sometimes associated with disease. Thus, detec...

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Detalles Bibliográficos
Autores principales: Niu, Liang, Huang, Weichun, Umbach, David M, Li, Leping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195885/
https://www.ncbi.nlm.nih.gov/pubmed/25283306
http://dx.doi.org/10.1186/1471-2164-15-862