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Vitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old wistar rats
BACKGROUND: The diminished ability of aged muscle to self-repair is a factor behind sarcopenia and contributes to muscle atrophy. Muscle repair depends on satellite cells whose pool size is diminished with aging. A reduction in Notch pathway activity may explain the age-related decrease in satellite...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195890/ https://www.ncbi.nlm.nih.gov/pubmed/25317198 http://dx.doi.org/10.1186/1743-7075-11-47 |