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Human endogenous retroviral elements promote genome instability via non-allelic homologous recombination
BACKGROUND: Recurrent rearrangements of the human genome resulting in disease or variation are mainly mediated by non-allelic homologous recombination (NAHR) between low-copy repeats. However, other genomic structures, including AT-rich palindromes and retroviruses, have also been reported to underl...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195946/ https://www.ncbi.nlm.nih.gov/pubmed/25246103 http://dx.doi.org/10.1186/s12915-014-0074-4 |