Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects

Ketamine, an N-methyl-D-aspartate receptor (NMDAR) channel blocker, has been found to induce rapid and robust antidepressant-like effects in rodent models and in treatment-refractory depressed patients. However, the marked acute psychological side effects of ketamine complicate the interpretation of...

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Detalles Bibliográficos
Autores principales: Sanacora, G, Smith, M A, Pathak, S, Su, H-L, Boeijinga, P H, McCarthy, D J, Quirk, M C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195977/
https://www.ncbi.nlm.nih.gov/pubmed/24126931
http://dx.doi.org/10.1038/mp.2013.130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195977/
https://www.ncbi.nlm.nih.gov/pubmed/24126931
http://dx.doi.org/10.1038/mp.2013.130

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