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Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8(+) T cells

BACKGROUND: Adoptive T cell therapy represents an attractive modality for the treatment of patients with cancer. Peripheral blood mononuclear cells have been used as a source of antigen specific T cells but the very low frequency of T cells recognizing commonly expressed antigens such as NY-ESO-1 li...

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Detalles Bibliográficos
Autores principales: Pollack, Seth M, Jones, Robin L, Farrar, Erik A, Lai, Ivy P, Lee, Sylvia M, Cao, Jianhong, Pillarisetty, Venu G, Hoch, Benjamin L, Gullett, Ashley, Bleakley, Marie, Conrad, Ernest U, Eary, Janet F, Shibuya, Kendall C, Warren, Edus H, Carstens, Jason N, Heimfeld, Shelly, Riddell, Stanley R, Yee, Cassian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196009/
https://www.ncbi.nlm.nih.gov/pubmed/25317334
http://dx.doi.org/10.1186/s40425-014-0036-y