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Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8(+) T cells
BACKGROUND: Adoptive T cell therapy represents an attractive modality for the treatment of patients with cancer. Peripheral blood mononuclear cells have been used as a source of antigen specific T cells but the very low frequency of T cells recognizing commonly expressed antigens such as NY-ESO-1 li...
Autores principales: | Pollack, Seth M, Jones, Robin L, Farrar, Erik A, Lai, Ivy P, Lee, Sylvia M, Cao, Jianhong, Pillarisetty, Venu G, Hoch, Benjamin L, Gullett, Ashley, Bleakley, Marie, Conrad, Ernest U, Eary, Janet F, Shibuya, Kendall C, Warren, Edus H, Carstens, Jason N, Heimfeld, Shelly, Riddell, Stanley R, Yee, Cassian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196009/ https://www.ncbi.nlm.nih.gov/pubmed/25317334 http://dx.doi.org/10.1186/s40425-014-0036-y |
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