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let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis
BACKGROUND: Aberrant AKT activation contributes to gastric cancer cell survival and chemotherapy resistance, however its regulation is poorly understood. microRNAs have been established to be important regulators in gastric carcinogenesis. Here, we showed the functional role and putative target of l...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196013/ https://www.ncbi.nlm.nih.gov/pubmed/25288334 http://dx.doi.org/10.1186/s12967-014-0281-3 |