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let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis

BACKGROUND: Aberrant AKT activation contributes to gastric cancer cell survival and chemotherapy resistance, however its regulation is poorly understood. microRNAs have been established to be important regulators in gastric carcinogenesis. Here, we showed the functional role and putative target of l...

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Detalles Bibliográficos
Autores principales: Kang, Wei, Tong, Joanna HM, Lung, Raymond WM, Dong, Yujuan, Yang, Weiqin, Pan, Yi, Lau, Kin Mang, Yu, Jun, Cheng, Alfred SL, To, Ka Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196013/
https://www.ncbi.nlm.nih.gov/pubmed/25288334
http://dx.doi.org/10.1186/s12967-014-0281-3