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Fluorescence activated enrichment of CD146+ cells during expansion of human bone-marrow derived mesenchymal stromal cells augments proliferation and GAG/DNA content in chondrogenic media

BACKGROUND: While numerous subpopulations of BM-MSCs have been identified, the relevance of these findings regarding the functional properties remains mostly unclear. With regards to attempts of enhancing differentiation results by preselecting certain MSC subtypes, we have evaluated the efficiency...

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Detalles Bibliográficos
Autores principales: Hagmann, Sebastien, Frank, Sebastian, Gotterbarm, Tobias, Dreher, Thomas, Eckstein, Volker, Moradi, Babak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196082/
https://www.ncbi.nlm.nih.gov/pubmed/25262357
http://dx.doi.org/10.1186/1471-2474-15-322