Protein Kinase D1 attenuates tumorigenesis in colon cancer by modulating β-catenin/T cell factor activity

Over 80% of colon cancer development and progression is a result of the dysregulation of β-catenin signaling pathway. Herein, for the first time, we demonstrate that a serine-threonine kinase, Protein Kinase D1 (PKD1), modulates the functions of β-catenin to suppress colon cancer growth. Analysis of...

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Detalles Bibliográficos
Autores principales: Sundram, Vasudha, Ganju, Aditya, Hughes, Joshua E., Khan, Sheema, Chauhan, Subhash C., Jaggi, Meena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196169/
https://www.ncbi.nlm.nih.gov/pubmed/25149539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196169/
https://www.ncbi.nlm.nih.gov/pubmed/25149539

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