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Protein Kinase D1 attenuates tumorigenesis in colon cancer by modulating β-catenin/T cell factor activity

Over 80% of colon cancer development and progression is a result of the dysregulation of β-catenin signaling pathway. Herein, for the first time, we demonstrate that a serine-threonine kinase, Protein Kinase D1 (PKD1), modulates the functions of β-catenin to suppress colon cancer growth. Analysis of...

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Detalles Bibliográficos
Autores principales:	Sundram, Vasudha, Ganju, Aditya, Hughes, Joshua E., Khan, Sheema, Chauhan, Subhash C., Jaggi, Meena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196169/ https://www.ncbi.nlm.nih.gov/pubmed/25149539

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