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Deletion of Ptprd and Cdkn2a cooperate to accelerate tumorigenesis

PTPRD encodes the protein tyrosine phosphatase receptor type D and is frequently inactivated across many human cancers. Despite its frequent inactivation, it is unknown whether loss of PTPRD promotes tumorigenesis in vivo. PTPRD is located on chromosome 9p, as is CDKN2A, and the two loci are frequen...

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Detalles Bibliográficos
Autores principales: Ortiz, Berenice, White, Julie R., Wu, Wei H., Chan, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196177/
https://www.ncbi.nlm.nih.gov/pubmed/25138050