Proteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer

The goal of this study was to determine whether combined targeted therapies, specifically those against the Notch, hedgehog and ubiquitin-proteasome pathways, could overcome ovarian cancer chemoresistance. Chemoresistant ovarian cancer cells were exposed to gamma-secretase inhibitors (GSI-I, Compoun...

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Detalles Bibliográficos
Autores principales: Steg, Adam D., Burke, Mata R., Amm, Hope M., Katre, Ashwini A., Dobbin, Zachary C., Jeong, Dae Hoon, Landen, Charles N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196184/
https://www.ncbi.nlm.nih.gov/pubmed/25216523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196184/
https://www.ncbi.nlm.nih.gov/pubmed/25216523

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