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Deubiquitinating enzyme Usp12 regulates the interaction between the androgen receptor and the Akt pathway

The androgen receptor (AR) is a transcription factor involved in prostate cell growth, homeostasis and transformation regulated by post-translational modifications, including ubiquitination. We have recently reported that AR is deubiquitinated and stabilised by Usp12 resulting in increased transcrip...

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Detalles Bibliográficos
Autores principales: McClurg, Urszula L., Summerscales, Emma E., Harle, Victoria J., Gaughan, Luke, Robson, Craig N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196185/
https://www.ncbi.nlm.nih.gov/pubmed/25216524