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Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors

Brain tumors, either primary (e.g., glioblastoma multiforme) or secondary (metastatic), remain among the most intractable and fatal of all cancers. We have shown that nanovesicles consisting of Saposin C (SapC) and dioleylphosphatidylserine (DOPS) are able to effectively target and kill cancer cells...

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Detalles Bibliográficos
Autores principales: Blanco, Víctor M., Chu, Zhengtao, Vallabhapurapu, Subrahmanya D., Sulaiman, Mahaboob K., Kendler, Ady, Rixe, Olivier, Warnick, Ronald E., Franco, Robert S., Qi, Xiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196187/
https://www.ncbi.nlm.nih.gov/pubmed/25051370