X-linked inhibitor of apoptosis protein (XIAP) lacking RING domain localizes to the nuclear and promotes cancer cell anchorage-independent growth by targeting the E2F1/Cyclin E axis

The inhibitor of apoptosis protein XIAP (X-linked inhibitor of apoptosis protein) is a well-documented protein that is located in cytoplasm acting as a potent regulator of cell apoptosis. Here, we showed that expressing XIAP with RING (Really Interesting New Gene) domain deletion (XIAP(ΔRING)) in ca...

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Detalles Bibliográficos
Autores principales: Cao, Zipeng, Li, Xueyong, Li, Jingxia, Luo, Wenjing, Huang, Chuanshu, Chen, Jingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196189/
https://www.ncbi.nlm.nih.gov/pubmed/25216527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196189/
https://www.ncbi.nlm.nih.gov/pubmed/25216527

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