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Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis

INTRODUCTION: Inflammation is a key pathological hallmark of several neurodegenerative disorders including Alzheimer’s disease, Parkinson’s disease and familial amyloidotic polyneuropathy (FAP). Among all inflammatory cytokines associated with FAP, IL-1β, in particular, has been implicated in playin...

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Detalles Bibliográficos
Autores principales: Gonçalves, Nádia Pereira, Vieira, Paulo, Saraiva, Maria João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa UK Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196507/
https://www.ncbi.nlm.nih.gov/pubmed/24918964
http://dx.doi.org/10.3109/13506129.2014.927759