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Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis
INTRODUCTION: Inflammation is a key pathological hallmark of several neurodegenerative disorders including Alzheimer’s disease, Parkinson’s disease and familial amyloidotic polyneuropathy (FAP). Among all inflammatory cytokines associated with FAP, IL-1β, in particular, has been implicated in playin...
Autores principales: | Gonçalves, Nádia Pereira, Vieira, Paulo, Saraiva, Maria João |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa UK Ltd.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196507/ https://www.ncbi.nlm.nih.gov/pubmed/24918964 http://dx.doi.org/10.3109/13506129.2014.927759 |
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