Non-viral gene therapy that targets motor neurons in vivo

A major challenge in neurological gene therapy is safe delivery of transgenes to sufficient cell numbers from the circulation or periphery. This is particularly difficult for diseases involving spinal cord motor neurons such as amyotrophic lateral sclerosis (ALS). We have examined the feasibility of...

Descripción completa

Detalles Bibliográficos
Autores principales: Rogers, Mary-Louise, Smith, Kevin S., Matusica, Dusan, Fenech, Matthew, Hoffman, Lee, Rush, Robert A., Voelcker, Nicolas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196515/
https://www.ncbi.nlm.nih.gov/pubmed/25352776
http://dx.doi.org/10.3389/fnmol.2014.00080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196515/
https://www.ncbi.nlm.nih.gov/pubmed/25352776
http://dx.doi.org/10.3389/fnmol.2014.00080

Ejemplares similares