Single-cell genetic expression of mutant GABA(A) receptors causing Human genetic epilepsy alters dendritic spine and GABAergic bouton formation in a mutation-specific manner

Mutations in genes encoding for GABA(A) receptor subunits is a well-established cause of genetic generalized epilepsy. GABA neurotransmission is implicated in several developmental processes including neurite outgrowth and synapse formation. Alteration in excitatory/inhibitory synaptic activities pl...

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Detalles Bibliográficos
Autores principales: Lachance-Touchette, Pamela, Choudhury, Mayukh, Stoica, Ana, Di Cristo, Graziella, Cossette, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196543/
https://www.ncbi.nlm.nih.gov/pubmed/25352779
http://dx.doi.org/10.3389/fncel.2014.00317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196543/
https://www.ncbi.nlm.nih.gov/pubmed/25352779
http://dx.doi.org/10.3389/fncel.2014.00317

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