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Single-cell genetic expression of mutant GABA(A) receptors causing Human genetic epilepsy alters dendritic spine and GABAergic bouton formation in a mutation-specific manner
Mutations in genes encoding for GABA(A) receptor subunits is a well-established cause of genetic generalized epilepsy. GABA neurotransmission is implicated in several developmental processes including neurite outgrowth and synapse formation. Alteration in excitatory/inhibitory synaptic activities pl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196543/ https://www.ncbi.nlm.nih.gov/pubmed/25352779 http://dx.doi.org/10.3389/fncel.2014.00317 |