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Tumour necrosis factor-α promotes liver ischaemia-reperfusion injury through the PGC-1α/Mfn2 pathway

Tumour necrosis factor (TNF)-α has been considered to induce ischaemia-reperfusion injury (IRI) of liver which is characterized by energy dysmetabolism. Peroxisome proliferator–activated receptor-γ co-activator (PGC)-1α and mitofusion2 (Mfn2) are reported to be involved in the regulation of mitochon...

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Detalles Bibliográficos
Autores principales: Li, Jun, Ke, Wenbo, Zhou, Qi, Wu, Yongzhong, Luo, Hong, Zhou, Hong, Yang, Bin, Guo, Yu, Zheng, Qichang, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196661/
https://www.ncbi.nlm.nih.gov/pubmed/24898700
http://dx.doi.org/10.1111/jcmm.12320