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Fibrillar β-amyloid 1-42 alters cytokine secretion, cholinergic signalling and neuronal differentiation

Adult neurogenesis is impaired by inflammatory processes, which are linked to altered cholinergic signalling and cognitive decline in Alzheimer's disease. In this study, we investigated how amyloid beta (Aβ)-evoked inflammatory responses affect the generation of new neurons from human embryonic...

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Detalles Bibliográficos
Autores principales: Malmsten, Linn, Vijayaraghavan, Swetha, Hovatta, Outi, Marutle, Amelia, Darreh-Shori, Taher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196662/
https://www.ncbi.nlm.nih.gov/pubmed/25109373
http://dx.doi.org/10.1111/jcmm.12343