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Fibrillar β-amyloid 1-42 alters cytokine secretion, cholinergic signalling and neuronal differentiation
Adult neurogenesis is impaired by inflammatory processes, which are linked to altered cholinergic signalling and cognitive decline in Alzheimer's disease. In this study, we investigated how amyloid beta (Aβ)-evoked inflammatory responses affect the generation of new neurons from human embryonic...
Autores principales: | Malmsten, Linn, Vijayaraghavan, Swetha, Hovatta, Outi, Marutle, Amelia, Darreh-Shori, Taher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196662/ https://www.ncbi.nlm.nih.gov/pubmed/25109373 http://dx.doi.org/10.1111/jcmm.12343 |
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