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Structural Investigation of the Transmembrane Domain of KCNE1 in Proteoliposomes

[Image: see text] KCNE1 is a single-transmembrane protein of the KCNE family that modulates the function of voltage-gated potassium channels, including KCNQ1. Hereditary mutations in KCNE1 have been linked to diseases such as long QT syndrome (LQTS), atrial fibrillation, sudden infant death syndrome...

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Detalles Bibliográficos
Autores principales: Sahu, Indra D., Kroncke, Brett M., Zhang, Rongfu, Dunagan, Megan M., Smith, Hubbell J., Craig, Andrew, McCarrick, Robert M., Sanders, Charles R., Lorigan, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196734/
https://www.ncbi.nlm.nih.gov/pubmed/25234231
http://dx.doi.org/10.1021/bi500943p