Cellular Intrinsic Mechanism Affecting the Outcome of AML Treated with Ara-C in a Syngeneic Mouse Model

The mechanisms underlying acute myeloid leukemia (AML) treatment failure are not clear. Here, we established a mouse model of AML by syngeneic transplantation of BXH-2 derived myeloid leukemic cells and developed an efficacious Ara-C-based regimen for treatment of these mice. We proved that leukemic...

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Detalles Bibliográficos
Autores principales: Zhao, Wenjun, Wei, Lirong, Tan, Dongming, Su, Guangsong, Zheng, Yanwen, He, Chao, Mao, Zhengwei J., Singleton, Timothy P., Yin, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196759/
https://www.ncbi.nlm.nih.gov/pubmed/25314317
http://dx.doi.org/10.1371/journal.pone.0109198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196759/
https://www.ncbi.nlm.nih.gov/pubmed/25314317
http://dx.doi.org/10.1371/journal.pone.0109198

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