Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry

Benign prostatic hyperplasia and prostate cancer can be treated with the 5α-reductase inhibitors, finasteride and dutasteride, when pharmacodynamic biomarkers are useful in assessing response. A novel method was developed to measure the substrates and products of 5α-reductases (testosterone, 5α-dihy...

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Detalles Bibliográficos
Autores principales: Upreti, Rita, Naredo, Gregorio, Faqehi, Abdullah M.M., Hughes, Katherine A., Stewart, Laurence H., Walker, Brian R., Homer, Natalie Z.M., Andrew, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196769/
https://www.ncbi.nlm.nih.gov/pubmed/25281165
http://dx.doi.org/10.1016/j.talanta.2014.07.087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196769/
https://www.ncbi.nlm.nih.gov/pubmed/25281165
http://dx.doi.org/10.1016/j.talanta.2014.07.087

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