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γδT Cells Are Prevalent in the Proximal Aorta and Drive Nascent Atherosclerotic Lesion Progression and Neutrophilia in Hypercholesterolemic Mice

Unique innate immunity-linked γδT cells have been seen in early human artery lesions, but their role in lesion development has received little attention. Here we investigated whether γδT cells modulate atherogenesis in apolipoprotein E-deficient (ApoE KO) mice. We found that γδT cell numbers were ma...

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Detalles Bibliográficos
Autores principales: Vu, Duc M., Tai, Albert, Tatro, Jeffrey B., Karas, Richard H., Huber, Brigitte T., Beasley, Debbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196850/
https://www.ncbi.nlm.nih.gov/pubmed/25313857
http://dx.doi.org/10.1371/journal.pone.0109416