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Caenorhabditis elegans chaperonin CCT/TRiC is required for actin and tubulin biogenesis and microvillus formation in intestinal epithelial cells

Intestinal epithelial cells have unique apical membrane structures, known as microvilli, that contain bundles of actin microfilaments. In this study, we report that Caenorhabditis elegans cytosolic chaperonin containing TCP-1 (CCT) is essential for proper formation of microvilli in intestinal cells....

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Detalles Bibliográficos
Autores principales: Saegusa, Keiko, Sato, Miyuki, Sato, Katsuya, Nakajima-Shimada, Junko, Harada, Akihiro, Sato, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196862/
https://www.ncbi.nlm.nih.gov/pubmed/25143409
http://dx.doi.org/10.1091/mbc.E13-09-0530