Loss of γ-cytoplasmic actin triggers myofibroblast transition of human epithelial cells

Transdifferentiation of epithelial cells into mesenchymal cells and myofibroblasts plays an important role in tumor progression and tissue fibrosis. Such epithelial plasticity is accompanied by dramatic reorganizations of the actin cytoskeleton, although mechanisms underlying cytoskeletal effects on...

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Detalles Bibliográficos
Autores principales: Lechuga, Susana, Baranwal, Somesh, Li, Chao, Naydenov, Nayden G., Kuemmerle, John F., Dugina, Vera, Chaponnier, Christine, Ivanov, Andrei I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196865/
https://www.ncbi.nlm.nih.gov/pubmed/25143399
http://dx.doi.org/10.1091/mbc.E14-03-0815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196865/
https://www.ncbi.nlm.nih.gov/pubmed/25143399
http://dx.doi.org/10.1091/mbc.E14-03-0815

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