Cargando…
Loss of γ-cytoplasmic actin triggers myofibroblast transition of human epithelial cells
Transdifferentiation of epithelial cells into mesenchymal cells and myofibroblasts plays an important role in tumor progression and tissue fibrosis. Such epithelial plasticity is accompanied by dramatic reorganizations of the actin cytoskeleton, although mechanisms underlying cytoskeletal effects on...
Autores principales: | Lechuga, Susana, Baranwal, Somesh, Li, Chao, Naydenov, Nayden G., Kuemmerle, John F., Dugina, Vera, Chaponnier, Christine, Ivanov, Andrei I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196865/ https://www.ncbi.nlm.nih.gov/pubmed/25143399 http://dx.doi.org/10.1091/mbc.E14-03-0815 |
Ejemplares similares
-
Nonredundant roles of cytoplasmic β- and γ-actin isoforms in regulation of epithelial apical junctions
por: Baranwal, Somesh, et al.
Publicado: (2012) -
Unique and redundant functions of cytoplasmic actins and nonmuscle myosin II isoforms at epithelial junctions
por: Ivanov, Andrei I., et al.
Publicado: (2022) -
Loss of β-Cytoplasmic Actin in the Intestinal Epithelium Increases Gut Barrier Permeability in vivo and Exaggerates the Severity of Experimental Colitis
por: Lechuga, Susana, et al.
Publicado: (2020) -
Novel mechanism of cytokine-induced disruption of epithelial barriers: Janus kinase and protein kinase D-dependent downregulation of junction protein expression
por: Naydenov, Nayden G., et al.
Publicado: (2013) -
Tumor promotion by γ and suppression by β non-muscle actin isoforms
por: Dugina, Vera, et al.
Publicado: (2015)