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Two Dictyostelium tyrosine kinase–like kinases function in parallel, stress-induced STAT activation pathways
When Dictyostelium cells are hyperosmotically stressed, STATc is activated by tyrosine phosphorylation. Unusually, activation is regulated by serine phosphorylation and consequent inhibition of a tyrosine phosphatase: PTP3. The identity of the cognate tyrosine kinase is unknown, and we show that two...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196871/ https://www.ncbi.nlm.nih.gov/pubmed/25143406 http://dx.doi.org/10.1091/mbc.E14-07-1182 |