A Dynamic View of Molecular Switch Behavior at Serotonin Receptors: Implications for Functional Selectivity

Functional selectivity is a property of G protein-coupled receptors that allows them to preferentially couple to particular signaling partners upon binding of biased agonists. Publication of the X-ray crystal structure of serotonergic 5-HT(1B) and 5-HT(2B) receptors in complex with ergotamine, a dru...

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Detalles Bibliográficos
Autores principales: Martí-Solano, Maria, Sanz, Ferran, Pastor, Manuel, Selent, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196896/
https://www.ncbi.nlm.nih.gov/pubmed/25313636
http://dx.doi.org/10.1371/journal.pone.0109312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196896/
https://www.ncbi.nlm.nih.gov/pubmed/25313636
http://dx.doi.org/10.1371/journal.pone.0109312

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