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Inferring Protein Modulation from Gene Expression Data Using Conditional Mutual Information

Systematic, high-throughput dissection of causal post-translational regulatory dependencies, on a genome wide basis, is still one of the great challenges of biology. Due to its complexity, however, only a handful of computational algorithms have been developed for this task. Here we present CINDy (C...

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Detalles Bibliográficos
Autores principales: Giorgi, Federico M., Lopez, Gonzalo, Woo, Jung H., Bisikirska, Brygida, Califano, Andrea, Bansal, Mukesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196905/
https://www.ncbi.nlm.nih.gov/pubmed/25314274
http://dx.doi.org/10.1371/journal.pone.0109569