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Inferring Protein Modulation from Gene Expression Data Using Conditional Mutual Information
Systematic, high-throughput dissection of causal post-translational regulatory dependencies, on a genome wide basis, is still one of the great challenges of biology. Due to its complexity, however, only a handful of computational algorithms have been developed for this task. Here we present CINDy (C...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196905/ https://www.ncbi.nlm.nih.gov/pubmed/25314274 http://dx.doi.org/10.1371/journal.pone.0109569 |