Cargando…

Timely Inhibition of Notch Signaling by DAPT Promotes Cardiac Differentiation of Murine Pluripotent Stem Cells

The Notch signaling pathway plays versatile roles during heart development. However, there is contradictory evidence that Notch pathway either facilitates or impairs cardiomyogenesis in vitro. In this study, we developed iPSCs by reprogramming of murine fibroblasts with GFP expression governed by Oc...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yinan, Li, Peng, Liu, Kaiyu, He, Qihua, Han, Shuo, Sun, Xiaofeng, Li, Tao, Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196912/
https://www.ncbi.nlm.nih.gov/pubmed/25313563
http://dx.doi.org/10.1371/journal.pone.0109588