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Mmu-miR-615-3p Regulates Lipoapoptosis by Inhibiting C/EBP Homologous Protein

Lipoapoptosis occurring due to an excess of saturated free fatty acids such as palmitate is a key pathogenic event in the initiation of nonalcoholic fatty liver disease. Palmitate loading of cells activates the endoplasmic reticulum stress response, including induction of the proapoptotic transcript...

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Detalles Bibliográficos
Autores principales: Miyamoto, Yasuhiro, Mauer, Amy S., Kumar, Swarup, Mott, Justin L., Malhi, Harmeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196923/
https://www.ncbi.nlm.nih.gov/pubmed/25314137
http://dx.doi.org/10.1371/journal.pone.0109637