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Mmu-miR-615-3p Regulates Lipoapoptosis by Inhibiting C/EBP Homologous Protein
Lipoapoptosis occurring due to an excess of saturated free fatty acids such as palmitate is a key pathogenic event in the initiation of nonalcoholic fatty liver disease. Palmitate loading of cells activates the endoplasmic reticulum stress response, including induction of the proapoptotic transcript...
Autores principales: | Miyamoto, Yasuhiro, Mauer, Amy S., Kumar, Swarup, Mott, Justin L., Malhi, Harmeet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196923/ https://www.ncbi.nlm.nih.gov/pubmed/25314137 http://dx.doi.org/10.1371/journal.pone.0109637 |
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