Copy Number Loss of the Interferon Gene Cluster in Melanomas Is Linked to Reduced T Cell Infiltrate and Poor Patient Prognosis

While immunotherapies are rapidly becoming mainstays of cancer treatment, significant gaps remain in our understanding of how to optimally target them, alone or in combination. Here we describe a novel method to monitor levels of immune cells and pathways in expression data from solid tumors using p...

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Detalles Bibliográficos
Autores principales: Linsley, Peter S., Speake, Cate, Whalen, Elizabeth, Chaussabel, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196925/
https://www.ncbi.nlm.nih.gov/pubmed/25314013
http://dx.doi.org/10.1371/journal.pone.0109760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196925/
https://www.ncbi.nlm.nih.gov/pubmed/25314013
http://dx.doi.org/10.1371/journal.pone.0109760

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