Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides: application to HIV genome

BACKGROUND: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequence variants. However, even for regions that are equally conserved, their potential utility as hybridization targets varie...

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Detalles Bibliográficos
Autores principales: Matveeva, Olga V, Foley, Brian T, Nemtsov, Vladimir A, Gesteland, Raymond F, Matsufuji, Senya, Atkins, John F, Ogurtsov, Alexei Y, Shabalina, Svetlana A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419695/
https://www.ncbi.nlm.nih.gov/pubmed/15115544
http://dx.doi.org/10.1186/1471-2105-5-44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419695/
https://www.ncbi.nlm.nih.gov/pubmed/15115544
http://dx.doi.org/10.1186/1471-2105-5-44

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