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Stimulators of Mineralization Limit the Invasive Phenotype of Human Osteosarcoma Cells by a Mechanism Involving Impaired Invadopodia Formation

BACKGROUND: Osteosarcoma (OS) is a highly aggressive bone cancer affecting children and young adults. Growing evidence connects the invasive potential of OS cells with their ability to form invadopodia (structures specialized in extracellular matrix proteolysis). RESULTS: In this study, we tested th...

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Detalles Bibliográficos
Autores principales: Cmoch, Anna, Podszywalow-Bartnicka, Paulina, Palczewska, Malgorzata, Piwocka, Katarzyna, Groves, Patrick, Pikula, Slawomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196965/
https://www.ncbi.nlm.nih.gov/pubmed/25314307
http://dx.doi.org/10.1371/journal.pone.0109938