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Lin28a Protects against Hypoxia/Reoxygenation Induced Cardiomyocytes Apoptosis by Alleviating Mitochondrial Dysfunction under High Glucose/High Fat Conditions

AIM: The aim of the present study was to investigate the role of Lin28a in protecting against hypoxia/reoxygenation (H/R)-induced cardiomyocytes apoptosis under high glucose/high fat (HG/HF) conditions. METHODS: Primary cardiomyocytes which were isolated from neonatal mouse were randomized to be tre...

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Detalles Bibliográficos
Autores principales: Zhang, Mingming, Niu, Xiaolin, Hu, Jianqiang, Yuan, Yuan, Sun, Shuhong, Wang, Jiaxing, Yu, Wenjun, Wang, Chen, Sun, Dongdong, Wang, Haichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196990/
https://www.ncbi.nlm.nih.gov/pubmed/25313561
http://dx.doi.org/10.1371/journal.pone.0110580