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Resveratrol Increases Nitric Oxide Production in the Rat Thick Ascending Limb via Ca(2+)/Calmodulin
The thick ascending limb of the loop of Henle reabsorbs 30% of the NaCl filtered through the glomerulus. Nitric oxide (NO) produced by NO synthase 3 (NOS3) inhibits NaCl absorption by this segment. Resveratrol, a polyphenol, has beneficial cardiovascular and renal effects, many of which are mediated...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196991/ https://www.ncbi.nlm.nih.gov/pubmed/25314136 http://dx.doi.org/10.1371/journal.pone.0110487 |