Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation

Kinetochores assemble on centromeric DNA and present arrays of proteins that attach directly to the dynamic ends of microtubules. Kinetochore proteins coordinate at the microtubule interface through oligomerization, but how oligomerization contributes to kinetochore function has remained unclear. He...

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Detalles Bibliográficos
Autores principales: Umbreit, Neil T., Miller, Matthew P., Tien, Jerry F., Cattin-Ortolá, Jérôme, Gui, Long, Lee, Kelly K., Biggins, Sue, Asbury, Charles L., Davis, Trisha N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197110/
https://www.ncbi.nlm.nih.gov/pubmed/25236177
http://dx.doi.org/10.1038/ncomms5951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197110/
https://www.ncbi.nlm.nih.gov/pubmed/25236177
http://dx.doi.org/10.1038/ncomms5951

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