Integrated Control Of Hepatic Lipogenesis Vs. Glucose Production Requires FoxO Transcription Factors

Insulin integrates hepatic glucose and lipid metabolism, directing nutrients to storage as glycogen and triglyceride. In type 2 diabetes, levels of the former are low and the latter are exaggerated, posing a pathophysiologic and therapeutic conundrum. A branching model of insulin signaling, with Fox...

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Detalles Bibliográficos
Autores principales: Haeusler, Rebecca A., Hartil, Kirsten, Vaitheesvaran, Bhavapriya, Arrieta–Cruz, Isabel, Knight, Colette M., Cook, Joshua R., Kammoun, Helene L., Febbraio, Mark A., Gutierrez–Juarez, Roger, Kurland, Irwin J., Accili, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197140/
https://www.ncbi.nlm.nih.gov/pubmed/25307742
http://dx.doi.org/10.1038/ncomms6190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197140/
https://www.ncbi.nlm.nih.gov/pubmed/25307742
http://dx.doi.org/10.1038/ncomms6190

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