Cargando…

Crystal structure of a eukaryotic group II intron lariat

The formation of branched lariat RNA is an evolutionarily conserved feature of splicing reactions for both group II and spliceosomal introns. The lariat is important for the fidelity of 5′ splice site selection and consists of a 2′-5′ phosphodiester bond between a bulged adenosine and the 5′ end of...

Descripción completa

Detalles Bibliográficos
Autores principales: Robart, Aaron R., Chan, Russell T., Peters, Jessica K., Rajashankar, Kanagalaghatta R., Toor, Navtej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197185/
https://www.ncbi.nlm.nih.gov/pubmed/25252982
http://dx.doi.org/10.1038/nature13790