A murine leukemia virus with Cre-LoxP excisible coding sequences allowing superinfection, transgene delivery, and generation of host genomic deletions

BACKGROUND: To generate a replication-competent retrovirus that could be conditionally inactivated, we flanked the viral genes of the Akv murine leukemia virus with LoxP sites. This provirus can delete its envelope gene by LoxP/Cre mediated recombination and thereby allow superinfection of Cre recom...

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Detalles Bibliográficos
Autores principales: Wang, Clifford L, Hodgson, J Graeme, Malek, Tiffany, Pedersen, Finn Skou, Wabl, Matthias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419723/
https://www.ncbi.nlm.nih.gov/pubmed/15169571
http://dx.doi.org/10.1186/1742-4690-1-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419723/
https://www.ncbi.nlm.nih.gov/pubmed/15169571
http://dx.doi.org/10.1186/1742-4690-1-5

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