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Two discrete events, human T-cell leukemia virus type I Tax oncoprotein expression and a separate stress stimulus, are required for induction of apoptosis in T-cells

BACKGROUND: It is poorly understood why many transforming proteins reportedly enhance both cell growth (transformation) and cell death (apoptosis). At first glance, the ability to transform and the ability to engender apoptosis seem to be contradictory. Interestingly, both abilities have been widely...

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Detalles Bibliográficos
Autores principales: Kasai, Takefumi, Jeang, Kuan-Teh
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419724/
https://www.ncbi.nlm.nih.gov/pubmed/15169569
http://dx.doi.org/10.1186/1742-4690-1-7