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KvarQ: targeted and direct variant calling from fastq reads of bacterial genomes

BACKGROUND: High-throughput DNA sequencing produces vast amounts of data, with millions of short reads that usually have to be mapped to a reference genome or newly assembled. Both reference-based mapping and de novo assembly are computationally intensive, generating large intermediary data files, a...

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Detalles Bibliográficos
Autores principales: Steiner, Andreas, Stucki, David, Coscolla, Mireia, Borrell, Sonia, Gagneux, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197298/
https://www.ncbi.nlm.nih.gov/pubmed/25297886
http://dx.doi.org/10.1186/1471-2164-15-881