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KvarQ: targeted and direct variant calling from fastq reads of bacterial genomes
BACKGROUND: High-throughput DNA sequencing produces vast amounts of data, with millions of short reads that usually have to be mapped to a reference genome or newly assembled. Both reference-based mapping and de novo assembly are computationally intensive, generating large intermediary data files, a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197298/ https://www.ncbi.nlm.nih.gov/pubmed/25297886 http://dx.doi.org/10.1186/1471-2164-15-881 |