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Recurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma

BACKGROUND: The identification of fusion genes such as SYT-SSX1/SSX2, PAX3-FOXO1, TPM3/TPM4-ALK and EWS-FLI1 in human sarcomas has provided important insight into the diagnosis and targeted therapy of sarcomas. No recurrent fusion has been reported in human osteosarcoma. METHODS: Transcriptome seque...

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Detalles Bibliográficos
Autores principales: Yang, Jilong, Annala, Matti, Ji, Ping, Wang, Guowen, Zheng, Hong, Codgell, David, Du, Xiaoling, Fang, Zhiwei, Sun, Baocun, Nykter, Matti, Chen, Kexin, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197299/
https://www.ncbi.nlm.nih.gov/pubmed/25300797
http://dx.doi.org/10.1186/s13045-014-0076-2